Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1499856 | 0.86 | ALDH1A1 (0.42) | TTRTSHRCYP3A4GAAALDH1A1 | |
| SCHEMBL434493 | 0.86 | CYP3A4 (0.48) | GABRA1GABRB2TSHRCYP3A4PIK3CA | |
| Sulfuric Acid SCHEMBL28847019 | 0.84 | ALDH1A1 (0.41) | TTRTSHRCYP3A4GAAALDH1A1 | |
| SCHEMBL2906795 | 0.84 | TTR (0.55) | TTRGABRA1GABRB2TSHRGAA | |
| Sulfuric Acid SCHEMBL9293766 | 0.80 | GABRA1 (0.44) | TTRGABRA1GABRB2CYP3A4GAA | |
| SCHEMBL27467770 | 0.79 | GAA (0.54) | TTRTSHRCYP3A4PIK3CAGAA | |
| SCHEMBL502321 | 0.79 | MMP2 (0.47) | GABRA1GABRB2ALDH1A1HSD17B10CA2 | |
| Sulfuric Acid SCHEMBL27823215 | 0.79 | ALDH1A1 (0.42) | TTRGABRA1GABRB2ALDH1A1HSD17B10 | |
| SCHEMBL4788421 | 0.78 | CA2 (0.55) | TTRGAAALDH1A1CA2CA12 | |
| SCHEMBL28136844 | 0.77 | CD44 (0.36) | TTRTSHRCYP3A4PIK3CAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838231-B2 | Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-01-04 | — | — | US | disclosed |
| US-6638705-B1 | Silver halide emulsion chemically sensitized by at least one compound having bond of anionic chalcogenide to gold(I) cation and capable of releasing gold-chalcogen anion species;high sensitivity, low fog, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-6496280-B2 | Method for image formation and apparatus for development processing | FUJI PHOTO FILM CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-6340560-B1 | USED IN A BLEACHING OR BLEACH-FIXING STEP AFTER THE TREATMENT WITH A COLOR DEVELOPER, PHOTOGRAPHY, STABILIZATION | FUJI PHOTO FILM CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| US-6221569-B1 | Method of forming color images and picture-taking color photographic material used therein | FUJI PHOTO FILM CO., LTD. (JP) | 2001-04-24 | — | — | US | disclosed |
| US-6207360-B1 | FIXING-OMITTED DEVELOPMENT PROCESSING, DESILVERING-OMITTED DEVELOPMENT PROCESSING OR BLEACHING-OMITTED DEVELOPMENT PROCESSING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6057090-A | Silver halide photographic material and hydroxamic acid-based compound used therefor | FUJI PHOTO FILM CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5976779-A | CONTAINING A METHINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |