Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29598045 | 1.00 | TSHR (0.43) | TSHRADAMTS5MMP2ADAM17MEN1 | |
| SCHEMBL1012052 | 1.00 | TSHR (0.43) | TSHRADAMTS5MMP2ADAM17MEN1 | |
| SCHEMBL29161773 | 0.83 | ADAMTS5 (0.40) | TSHRADAMTS5MMP2ADAM17MEN1 | |
| SCHEMBL41056 | 0.83 | ADAMTS5 (0.40) | TSHRADAMTS5MMP2ADAM17MEN1 | |
| SCHEMBL163425 | 0.81 | MEN1 (0.41) | MEN1KMT2AGAAHTTPAX8 | |
| SCHEMBL2867325 | 0.81 | MEN1 (0.41) | MEN1KMT2AGAAHTTPAX8 | |
| D-Leucine SCHEMBL11435084 | 0.81 | SLC7A5 (0.51) | TSHRADAMTS5MMP2ADAM17GAA | |
| Leucine SCHEMBL11083186 | 0.81 | SLC7A5 (0.51) | TSHRADAMTS5MMP2ADAM17GAA | |
| Leucine SCHEMBL11083182 | 0.81 | SLC7A5 (0.51) | TSHRADAMTS5MMP2ADAM17GAA | |
| SCHEMBL13167432 | 0.79 | MEN1 (0.38) | MEN1KMT2AGAAHTTPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |
| EP-4196220-A1 | TRIAZOLE-PYRIDINYL SUBSTITUTED AZACYCLOHEXYL ACETIC ACID COMPOUNDS AS LPA RECEPTOR ANTAGONISTS | Viva Star Biosciences Limited (HK) | 2023-06-21 | — | — | EP | disclosed |