Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL11083186 | 1.00 | SLC7A5 (0.51) | SLC7A5SLC1A3SLC1A2IDO1TDO2 | |
| D-Leucine SCHEMBL11435084 | 1.00 | SLC7A5 (0.51) | SLC7A5SLC1A3SLC1A2IDO1TDO2 | |
| Norleucine SCHEMBL9839120 | 0.84 | AGER (0.43) | SLC1A3SLC1A2IDO1TDO2ADAMTS5 | |
| SCHEMBL29598045 | 0.81 | TSHR (0.43) | ADAMTS5MMP2ADAM17GAATSHR | |
| SCHEMBL29067975 | 0.81 | TSHR (0.43) | ADAMTS5MMP2ADAM17GAATSHR | |
| SCHEMBL1012052 | 0.81 | TSHR (0.43) | ADAMTS5MMP2ADAM17GAATSHR | |
| SCHEMBL17884949 | 0.77 | ADAMTS5 (0.49) | ADAMTS5MMP2ADAM17GAATSHR | |
| SCHEMBL27806252 | 0.75 | GAA (0.38) | SLC1A3SLC1A2IDO1TDO2ADAMTS5 | |
| Leucine SCHEMBL25241602 | 0.72 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL331557 | 0.72 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436910-A | SAPONIFICATION | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |