Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581647 | 0.83 | SLC18A3 (0.48) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL6599138 | 0.82 | SLC18A3 (0.47) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL25255721 | 0.81 | CYP1A2 (0.46) | CYP1A2CYP2D6FAAHMGLL | |
| SCHEMBL25279026 | 0.80 | ALDH1A1 (0.54) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL2748801 | 0.80 | ALDH1A1 (0.71) | CYP1A2CYP2D6FAAHPOLBMGLL | |
| SCHEMBL27727100 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP2D6FAAHMEN1POLB | |
| SCHEMBL28539303 | 0.79 | RIPK1 (0.47) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL31421732 | 0.78 | ALDH1A1 (0.44) | MEN1POLBKMT2AMGLLALDH1A1 | |
| SCHEMBL28408689 | 0.78 | ALDH1A1 (0.54) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL18424173 | 0.77 | CYP1A2 (0.73) | CYP1A2CYP2D6FAAHMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |