Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2971835 | 0.79 | LTA4H (0.38) | KCNH2 | |
| SCHEMBL28489132 | 0.78 | SMN1; SMN2 (0.38) | KCNH2 | |
| SCHEMBL2968624 | 0.77 | NPC1 (0.38) | KCNH2 | |
| SCHEMBL23652 | 0.74 | NFE2L2 (0.33) | — | |
| SCHEMBL2974066 | 0.73 | L3MBTL1 (0.37) | KCNH2 | |
| SCHEMBL27997690 | 0.73 | FFAR1 (0.33) | FFAR1 | |
| SCHEMBL28473733 | 0.73 | MKNK1 (0.32) | FFAR1KCNH2 | |
| SCHEMBL9723567 | 0.70 | L3MBTL1 (0.31) | — | |
| SCHEMBL2105809 | 0.70 | EPHX2 (0.36) | — | |
| SCHEMBL29068556 | 0.70 | FFAR1 (0.36) | KCNJ5KCNJ3FFAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |