Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572925 | 1.00 | ALOX15 (0.35) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL9464895 | 0.84 | CES2 (0.37) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL4868822 | 0.80 | TSHR (0.46) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL11039041 | 0.77 | PDE2A (0.33) | CES2NOTUMGABRB3 | |
| SCHEMBL23899710 | 0.77 | CHEK1 (0.37) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL22119936 | 0.77 | HPGD (0.37) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL10699329 | 0.77 | TSHR (0.58) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL13550140 | 0.76 | GABRB3 (0.37) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL15729337 | 0.74 | TSHR (0.45) | ALOX15ALOX12CES2ALDH1A1CYP3A4 | |
| SCHEMBL9217763 | 0.74 | ALDH1A1 (0.43) | CES2ALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744918-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-09-12 | — | — | CN | disclosed |