Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881371 | 0.78 | TSHR (0.38) | ALDH1A1LMNATDP1RECQLHSD17B10 | |
| SCHEMBL8410970 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C9KMT2AGAAALDH1A1 | |
| SCHEMBL2546 | 0.77 | LMNA (0.53) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL29024318 | 0.77 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL4344155 | 0.76 | CYP2D6 (0.41) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL29070867 | 0.75 | STAT3 (0.41) | KMT2AGAAALDH1A1MEN1SMN1; SMN2 | |
| Tert-Butylamine SCHEMBL2724638 | 0.73 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL8505195 | 0.72 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL2942435 | 0.72 | CYP2D6 (0.43) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A | |
| SCHEMBL757056 | 0.71 | GBA1 (0.53) | CYP1A2CYP2C9CYP2D6MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332996-B | L-ribofuranose type anti-coronavirus compound, and preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-116332996-A | Anti-coronavirus compound, preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |