Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30283138 | 0.80 | PARP1 (0.40) | PARP1MAPK1POLBGPR119LMNA | |
| SCHEMBL29182722 | 0.80 | PARP1 (0.40) | PARP1MAPK1POLBGPR119LMNA | |
| SCHEMBL17560446 | 0.80 | PARP1 (0.41) | PARP1MAPK1GPR119MC4RMC5R | |
| SCHEMBL28978028 | 0.79 | MAPK1 (0.43) | PARP1MAPK1KDM4EGPR119MC4R | |
| SCHEMBL30740797 | 0.74 | PARP1 (0.38) | PARP1MAPK1POLBKDM4EMC4R | |
| SCHEMBL27701654 | 0.74 | SLC6A2 (0.43) | PARP1MAPK1MEN1KMT2A | |
| SCHEMBL18228700 | 0.74 | GPR119 (0.51) | POLBGPR119USP30KMT2A | |
| SCHEMBL28067177 | 0.73 | GPR119 (0.47) | PARP1GPR119MC4RMC5RNPC1 | |
| SCHEMBL1115469 | 0.73 | LMNA (0.41) | PARP1POLBGPR119MC4RMC5R | |
| SCHEMBL1685922 | 0.73 | HSD17B10 (0.47) | PARP1MAPK1MC4RMC5RNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |