Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC5R | P33032 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560446 | 0.85 | PARP1 (0.41) | PARP1UCHL1NPC1USP30MAPK1 | |
| SCHEMBL28978028 | 0.80 | MAPK1 (0.43) | PARP1UCHL1NPC1MAPK1MC4R | |
| SCHEMBL1115469 | 0.78 | LMNA (0.41) | PARP1UCHL1NPC1LMNANPSR1 | |
| SCHEMBL28067177 | 0.76 | GPR119 (0.47) | PARP1UCHL1NPC1MC4RMC5R | |
| SCHEMBL29072017 | 0.74 | PARP1 (0.39) | PARP1UCHL1NPC1USP30MAPK1 | |
| SCHEMBL29574894 | 0.73 | CXCR4 (0.36) | PARP1UCHL1MAPK1LMNAHRH2 | |
| SCHEMBL3294559 | 0.73 | MEN1 (0.54) | LMNAPOLB | |
| SCHEMBL31498777 | 0.72 | GPR119 (0.32) | PARP1UCHL1USP30KDM2BPOLB | |
| SCHEMBL2480988 | 0.71 | HSD17B10 (0.47) | PARP1NPC1MAPK1LMNANPSR1 | |
| SCHEMBL1685922 | 0.71 | HSD17B10 (0.47) | PARP1NPC1MAPK1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |