Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797116 | 0.87 | GPR119 (0.49) | THRBHTTUBE2MDCUN1D1CCR5 | |
| SCHEMBL2791118 | 0.85 | THRB (0.45) | THRBOPRM1HTTUBE2MDCUN1D1 | |
| SCHEMBL2794952 | 0.85 | HTT (0.45) | THRBOPRM1CHRM3HTTCYP2C19 | |
| Hydrochloric Acid SCHEMBL2791119 | 0.84 | THRB (0.44) | THRBOPRM1OPRD1OPRK1HTT | |
| Hydrochloric Acid SCHEMBL2791115 | 0.84 | THRB (0.44) | THRBOPRM1OPRD1OPRK1HTT | |
| Hydrochloric Acid SCHEMBL2794947 | 0.84 | HTT (0.45) | THRBOPRM1CHRM3HTTCYP2C19 | |
| SCHEMBL784814 | 0.81 | CCR5 (0.60) | CCR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30802466 | 0.81 | SMN1; SMN2 (0.49) | CHRM2CHRM3CCR5NPC1RAB9A | |
| SCHEMBL2795154 | 0.81 | HTR2A (0.51) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL2795045 | 0.80 | KMT2A (0.44) | THRBUBE2MDCUN1D1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164829-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150089-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |