Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CCR5 | P51681 | 15/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32691106 | 0.90 | CCR6 (0.46) | SMN1; SMN2NPC1RAB9ACCR5CHRM2 | |
| SCHEMBL784814 | 0.88 | CCR5 (0.60) | SMN1; SMN2NPC1RAB9ACCR5 | |
| SCHEMBL7813133 | 0.87 | ENPP2 (0.51) | CCR5CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30802348 | 0.87 | GPR119 (0.49) | SMN1; SMN2NPC1RAB9ACCR5 | |
| SCHEMBL30802476 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 | |
| SCHEMBL13641301 | 0.84 | SIGMAR1 (0.46) | CCR5CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL10325504 | 0.84 | SIGMAR1 (0.46) | CCR5CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL30802298 | 0.84 | SLC6A2 (0.45) | CCR5CHRM3 | |
| SCHEMBL31076054 | 0.83 | HSD11B1 (0.53) | SMN1; SMN2NPC1RAB9ACCR5 | |
| SCHEMBL2795154 | 0.82 | HTR2A (0.51) | SMN1; SMN2NPC1RAB9ACCR5CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |