Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912544 | 0.88 | CYP19A1 (0.37) | GSK3AGSK3BCDK1 | |
| SCHEMBL2912527 | 0.87 | GSK3B (0.36) | GSK3AGSK3BKAT2BCDK1 | |
| SCHEMBL2908407 | 0.87 | GSK3B (0.34) | GSK3AGSK3BKAT2BCDK1 | |
| SCHEMBL2907498 | 0.86 | RAB9A (0.38) | GSK3AGSK3B | |
| SCHEMBL2904881 | 0.86 | RAB9A (0.39) | GSK3AGSK3B | |
| SCHEMBL2912926 | 0.85 | BDKRB1 (0.34) | GSK3AGSK3BKAT2B | |
| SCHEMBL2939108 | 0.85 | GSK3B (0.45) | GSK3AGSK3BCDK1 | |
| SCHEMBL2910394 | 0.84 | KDM4E (0.39) | GSK3B | |
| SCHEMBL2910651 | 0.84 | MAPT (0.36) | — | |
| SCHEMBL2913211 | 0.83 | POLB (0.46) | GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |