Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911203 | 0.90 | CSF1R (0.56) | CSF1RMAPTEGFRKCNH2SCN5A | |
| SCHEMBL2912772 | 0.87 | MAPT (0.46) | CSF1RMAPTEGFRKCNH2SCN5A | |
| SCHEMBL2911700 | 0.86 | KCNH2 (0.51) | CSF1RMAPTEGFRKCNH2SCN5A | |
| SCHEMBL2908706 | 0.84 | KCNH2 (0.46) | CSF1RMAPTEGFRKCNH2SCN5A | |
| SCHEMBL2909948 | 0.81 | CSF1R (0.73) | CSF1RKCNH2SCN5A | |
| SCHEMBL2905929 | 0.81 | CSF1R (0.53) | CSF1RKCNH2SCN5AERBB2 | |
| SCHEMBL2907516 | 0.81 | CSF1R (0.60) | CSF1RMAPTEGFRKCNH2SCN5A | |
| SCHEMBL2912641 | 0.80 | CSF1R (0.60) | CSF1RKCNH2SCN5AERBB2 | |
| SCHEMBL2913453 | 0.78 | CSF1R (0.73) | CSF1RKCNH2SCN5A | |
| SCHEMBL2905235 | 0.78 | KCNH2 (0.61) | CSF1RMAPTEGFRKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |