Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MYD88 | Q99836 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078389 | 0.90 | MYD88 (0.60) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL29078413 | 0.88 | LMNA (0.60) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL29078372 | 0.87 | ALDH1A1 (0.61) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30585261 | 0.87 | ALDH1A1 (0.61) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL30585251 | 0.86 | MEN1 (0.65) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL29078382 | 0.86 | MEN1 (0.65) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL29078361 | 0.79 | MYD88 (0.55) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL29078402 | 0.75 | ALDH1A1 (0.62) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL30585270 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2APOLBPABPC1LMNA | |
| SCHEMBL3147424 | 0.74 | ALDH1A1 (0.60) | MEN1KMT2APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |