Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | OGA | O60502 | 1/20 | 0.57 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078372 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EOGAREV1MEN1 | |
| SCHEMBL29078382 | 0.90 | MEN1 (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30585251 | 0.90 | MEN1 (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29078394 | 0.87 | MEN1 (0.60) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29078389 | 0.80 | MYD88 (0.60) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29078402 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30585253 | 0.77 | TSHR (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22516942 | 0.76 | LSS (0.65) | ALDH1A1KDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL12244095 | 0.76 | ACHE (0.58) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30585252 | 0.76 | OGA (0.51) | ALDH1A1KDM4EOGAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-116803981-A | Piperazine-containing amide or sulfonamide anti-inflammatory compound and preparation method and application thereof | 温州医科大学 | 2023-09-26 | — | — | CN | disclosed |