Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15416821 | 0.85 | KDR (0.47) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL31356515 | 0.74 | IDO1 (0.53) | KDRAURKAHDAC6NPC1FYN | |
| SCHEMBL12469844 | 0.74 | ADORA2A (0.44) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL30782031 | 0.74 | IDO1 (0.52) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL4602986 | 0.74 | AURKA (0.41) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL24696655 | 0.74 | CDK2 (0.42) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL86365 | 0.74 | ALDH1A1 (0.52) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL6335721 | 0.74 | CYP2A6 (0.44) | KDRAURKAADRA1DADRA1AADRA1B | |
| SCHEMBL2870174 | 0.74 | IDO1 (0.53) | KDRAURKAHDAC6NPC1FYN | |
| SCHEMBL30867600 | 0.74 | ALDH1A1 (0.52) | KDRAURKAADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640141-A | Preparation method of quinoxalinone compound | 浙江理工大学 | 2023-08-25 | — | — | CN | claimed |
| CN-119390699-A | Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound | 重庆文理学院 | 2025-02-07 | — | — | CN | disclosed |
| CN-116640141-A | Preparation method of quinoxalinone compound | 浙江理工大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116640141-A | Preparation method of quinoxalinone compound | 浙江理工大学 | 2023-08-25 | — | — | CN | disclosed |