Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391918 | 0.88 | MAPT (0.41) | AAK1SRCALDH1A1MAPTGAA | |
| SCHEMBL27391921 | 0.85 | ALDH1A1 (0.43) | SRCALDH1A1MAPTGAANPC1 | |
| SCHEMBL29079182 | 0.83 | AAK1 (0.47) | AAK1SRCALDH1A1MAPTEPHX2 | |
| SCHEMBL29079137 | 0.82 | AAK1 (0.42) | AAK1ALDH1A1MAPTGAAGSTP1 | |
| SCHEMBL29079146 | 0.81 | AAK1 (0.43) | AAK1ALDH1A1MAPTPDCD1CD274 | |
| SCHEMBL27372377 | 0.81 | ALDH1A1 (0.42) | SRCALDH1A1MAPTGAANPC1 | |
| SCHEMBL17540253 | 0.77 | MAPT (0.45) | AAK1SRCALDH1A1MAPTGAA | |
| SCHEMBL10456648 | 0.77 | EPHX2 (0.46) | ALDH1A1MAPTGAANPC1RAB9A | |
| SCHEMBL15964631 | 0.75 | AAK1 (0.50) | AAK1ALDH1A1GSTP1GSTM2 | |
| SCHEMBL29079129 | 0.75 | AAK1 (0.50) | AAK1ALDH1A1GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640156-A | RIPK1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-08-25 | — | — | CN | disclosed |