Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079137 | 0.91 | AAK1 (0.42) | AAK1PDK1ALDH1A1MAPT | |
| SCHEMBL8904841 | 0.88 | ALDH1A1 (0.40) | AAK1PDK1PPARGPPARACTSS | |
| SCHEMBL27391920 | 0.88 | ALDH1A1 (0.40) | AAK1PDK1PPARGPPARACTSS | |
| SCHEMBL1561567 | 0.88 | ALDH1A1 (0.40) | AAK1PDK1PPARGPPARACTSS | |
| SCHEMBL8904838 | 0.88 | ALDH1A1 (0.40) | AAK1PDK1PPARGPPARACTSS | |
| SCHEMBL1561729 | 0.86 | MAPT (0.53) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL8903187 | 0.85 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL9221220 | 0.85 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL7346992 | 0.85 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL1562131 | 0.85 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640156-A | RIPK1 inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-08-25 | — | — | CN | disclosed |