Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079158 | 0.93 | TSHR (0.44) | TSHRLMNANPSR1MAPTABCC9 | |
| SCHEMBL26970373 | 0.90 | NOTUM (0.39) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29079165 | 0.83 | KDM4E (0.54) | TSHRLMNANPSR1ABCC9ABCC8 | |
| SCHEMBL24477889 | 0.78 | KDM4E (0.59) | TSHRLMNANPSR1ABCC9ABCC8 | |
| SCHEMBL30483543 | 0.78 | KDM4E (0.59) | TSHRLMNANPSR1ABCC9ABCC8 | |
| SCHEMBL26970372 | 0.77 | KMO (0.39) | ABCC9ABCC8KCNJ11KCNJ8ATM | |
| SCHEMBL29079190 | 0.71 | GAA (0.56) | LMNAMAPTATMMEN1KMT2A | |
| SCHEMBL7102192 | 0.70 | ABCC9 (0.50) | TSHRMAPTABCC9ABCC8KCNJ11 | |
| SCHEMBL29079159 | 0.70 | KDM4E (0.46) | ATMMEN1KMT2A | |
| SCHEMBL7881090 | 0.68 | TSHR (0.59) | TSHRLMNANPSR1MAPTABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601145-A | Potent and selective calcium-activated potassium channel K for plateau treatment Ca 3.1 inhibitors | 南洋理工大学 | 2023-08-15 | — | — | CN | disclosed |