Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477918 | 0.95 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL29579441 | 0.95 | KDM4E (0.50) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL26970374 | 0.90 | ASPH (0.32) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL29079165 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL24477888 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL30483543 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL24477889 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL29079190 | 0.81 | GAA (0.56) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL29079175 | 0.75 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL26970372 | 0.75 | KMO (0.39) | KDM4EALDH1A1GAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601145-A | Potent and selective calcium-activated potassium channel K for plateau treatment Ca 3.1 inhibitors | 南洋理工大学 | 2023-08-15 | — | — | CN | disclosed |