Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483542 | 0.95 | GAA (0.61) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL24477898 | 0.95 | GAA (0.61) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL26970371 | 0.91 | HTR3E (0.42) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29079165 | 0.87 | KDM4E (0.54) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL30483543 | 0.82 | KDM4E (0.59) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL24477889 | 0.82 | KDM4E (0.59) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL24477920 | 0.81 | GAA (0.46) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29079159 | 0.81 | KDM4E (0.46) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL29079175 | 0.79 | ALDH1A1 (0.60) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL28854608 | 0.79 | HPGD (0.89) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116601145-A | Potent and selective calcium-activated potassium channel K for plateau treatment Ca 3.1 inhibitors | 南洋理工大学 | 2023-08-15 | — | — | CN | disclosed |