Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 6/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178254 | 0.75 | CRHR1 (0.42) | DRD1CRHR1L3MBTL1 | |
| SCHEMBL12326180 | 0.74 | CA1 (0.50) | MEN1KMT2AHTR3EHTR3BHTR3A | |
| SCHEMBL10563856 | 0.72 | ALDH1A1 (0.44) | KMT2ADRD1CRHR1RAD52L3MBTL1 | |
| SCHEMBL29534401 | 0.71 | DRD1 (0.40) | MEN1KMT2ADRD1CRHR1TLR8 | |
| SCHEMBL24343780 | 0.71 | DRD1 (0.40) | MEN1KMT2ADRD1CRHR1TLR8 | |
| SCHEMBL10568492 | 0.70 | CRHR1 (0.40) | CRHR1TLR8RAD52HTR3EHTR3B | |
| SCHEMBL14301863 | 0.69 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL29079836 | 0.68 | KMT2A (0.43) | KMT2AHTR3A | |
| SCHEMBL29079923 | 0.68 | DYRK1A (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL679848 | 0.67 | SMN1; SMN2 (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019388-A | 5-And 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 英莱汶公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-116648453-A | 5-and 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 活力疗法公司 | 2023-08-25 | — | — | CN | disclosed |