Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079836 | 0.85 | KMT2A (0.43) | KMT2AAMY1AHSD11B1ALDH1A1CA12 | |
| SCHEMBL29079869 | 0.80 | NQO2 (0.40) | KMT2AMAPTMEN1POLBALOX15 | |
| SCHEMBL29079788 | 0.77 | NQO2 (0.39) | KMT2AMAPTMEN1POLBALOX15 | |
| SCHEMBL7921177 | 0.74 | CA1 (0.52) | KMT2AMAPTMEN1ALOX15L3MBTL1 | |
| SCHEMBL29079800 | 0.73 | RPS6KA2 (0.37) | POLBL3MBTL1NQO2LMNAHPGD | |
| SCHEMBL29079889 | 0.73 | AMY1A (0.39) | AMY1A | |
| SCHEMBL29079843 | 0.71 | ALDH1A1 (0.41) | KMT2AMAPTMEN1POLBRECQL | |
| SCHEMBL31276627 | 0.71 | ADRB2 (0.41) | POLBL3MBTL1HPGDKCNN4 | |
| SCHEMBL24343762 | 0.70 | AMY1A (0.36) | DYRK1AKMT2AMEN1POLBNQO2 | |
| SCHEMBL29079816 | 0.68 | MEN1 (0.39) | KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019388-A | 5-And 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 英莱汶公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-116648453-A | 5-and 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 活力疗法公司 | 2023-08-25 | — | — | CN | disclosed |