Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 3/20 | 0.36 |
| ▸ | CLK3 | P49761 | 3/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079881 | 0.87 | DAO (0.49) | DAOHRH4MAPTSNCACLK2 | |
| SCHEMBL3141113 | 0.75 | DAO (0.51) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL5565498 | 0.75 | FLT3 (0.44) | DAOMAPTCYP2C9 | |
| SCHEMBL30960885 | 0.75 | FLT3 (0.44) | DAOMAPTCYP2C9 | |
| SCHEMBL28761709 | 0.74 | DAO (0.50) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL4033217 | 0.74 | DAO (0.50) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL1853725 | 0.67 | DAO (0.53) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL20004291 | 0.67 | DAO (0.53) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL31691908 | 0.67 | DAO (0.53) | DAOPDE3BPDE3AHRH4MAPT | |
| SCHEMBL28809999 | 0.67 | DAO (0.53) | DAOPDE3BPDE3AHRH4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648453-A | 5-and 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 活力疗法公司 | 2023-08-25 | — | — | CN | disclosed |