SCHEMBL29079987

SCHEMBL29079987

COc1ccc(C2=CC(=O)N(S(=O)(=O)c3ccc(C)cc3)CC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.51
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
NPC1 O15118 1/20 0.48
PKM P14618 1/20 0.48
PKLR P30613 1/20 0.48
RAB9A P51151 1/20 0.48
MAPT P10636 3/20 0.46
HSD11B1 P28845 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 2/20 0.46
USP2 O75604 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29080002 0.91 MMP2 (0.53) MMP2ALDH1A1PKMMAPTHSD11B1
SCHEMBL29822774 0.85 LMNA (0.61) MMP2KDM4EALDH1A1PKMMAPT
SCHEMBL29079971 0.85 MMP2 (0.47) MMP2ALDH1A1PKMMAPTHSD11B1
SCHEMBL29079975 0.85 MMP2 (0.47) MMP2KDM4EALDH1A1PKMMAPT
SCHEMBL29080011 0.84 HSD11B1 (0.56) MMP2KDM4EALDH1A1PKMMAPT
SCHEMBL29079985 0.82 MMP2 (0.44) MMP2ALDH1A1PKMMAPTHSD11B1
SCHEMBL29822623 0.82 MMP2 (0.44) MMP2ALDH1A1PKMMAPTHSD11B1
SCHEMBL29079986 0.76 MMP2 (0.46) MMP2ALDH1A1PKMMAPTHSD11B1
SCHEMBL29822938 0.74 MMP2 (0.50) MMP2KDM4EALDH1A1NPC1PKM
SCHEMBL29079998 0.74 NPC1 (0.48) MMP2KDM4ENPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853664-B Method for synthesizing alpha, beta-unsaturated cyclohexyl ketone compound under palladium catalysis condition 河南大学 2023-09-29 CN disclosed
CN-114853664-A Method for synthesizing alpha, beta-unsaturated heterocyclic hexyl ketone compound under palladium catalysis condition 河南大学 2022-08-05 CN disclosed