SCHEMBL29080282

SCHEMBL29080282

C=CCC#Cc1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 2/20 0.43
LMNA P02545 2/20 0.43
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
GRM5 P41594 2/20 0.39
CYP2A6 P11509 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
FFAR1 O14842 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29080306 0.79 PYCR1 (0.37) LMNACYP2A6ACACB
SCHEMBL29080275 0.79 LMNA (0.42) KCNH2MEN1KMT2AMAPTLMNA
SCHEMBL29080255 0.79 FFAR1 (0.37) LMNASMN1; SMN2GRM5FFAR1CHRM2
SCHEMBL29080261 0.79 CYP2A6 (0.39) KCNH2ALDH1A1LMNACYP2A6CA12
SCHEMBL2117815 0.78 CYP1A2 (0.52) MEN1KMT2APOLBALDH1A1MAPT
SCHEMBL29080251 0.77 GRM5 (0.46) HTTSMN1; SMN2GRM5CA12CA1
SCHEMBL17578918 0.73 KCNH2 (0.55) KCNH2MEN1KMT2APOLBALDH1A1
SCHEMBL29114228 0.71 GRM5 (0.43) KCNH2MEN1KMT2APOLBALDH1A1
SCHEMBL1066892 0.71 KCNH2 (0.53) KCNH2MEN1KMT2APOLBALDH1A1
SCHEMBL7038938 0.71 CYP2C19 (0.60) KCNH2MEN1KMT2APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490567-A 1, 3-eneyne compound synthesized by copper catalysis and synthesis method thereof 西安交通大学 2022-12-20 CN disclosed