SCHEMBL29080261

SCHEMBL29080261

C=CCC#Cc1ccc(C#N)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.39
LOXL2 Q9Y4K0 2/20 0.39
ALDH1A1 P00352 2/20 0.38
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TSHR P16473 1/20 0.36
MMP3 P08254 1/20 0.34
ENPP2 Q13822 1/20 0.34
GSK3B P49841 1/20 0.33
CYP19A1 P11511 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MAOB P27338 2/20 0.32
KCNJ1 P48048 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29080306 0.79 PYCR1 (0.37) CYP2A6MAOBLMNAMAOA
SCHEMBL29080275 0.79 LMNA (0.42) CYP2A6KCNH2KDM4ELMNA
SCHEMBL29080282 0.79 KCNH2 (0.44) CYP2A6ALDH1A1CA2CA12CA9
SCHEMBL29080255 0.79 FFAR1 (0.37) MAOBLMNAMAOA
SCHEMBL2117815 0.78 CYP1A2 (0.52) ALDH1A1TSHRHRH3KDM4ELMNA
SCHEMBL28230959 0.77 CYP1A2 (0.50) ALDH1A1TSHRHRH3KDM4ELMNA
SCHEMBL21623418 0.71 CYP2A6 (0.43) CYP2A6LOXL2ALDH1A1CA2CA12
SCHEMBL21623467 0.71 CYP2A6 (0.43) CYP2A6LOXL2ALDH1A1CA2CA12
SCHEMBL78831 0.71 CA2 (0.48) CYP2A6LOXL2ALDH1A1CA2CA12
SCHEMBL6029535 0.71 CYP2A6 (0.43) CYP2A6LOXL2ALDH1A1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490567-A 1, 3-eneyne compound synthesized by copper catalysis and synthesis method thereof 西安交通大学 2022-12-20 CN disclosed