SCHEMBL29080438

SCHEMBL29080438

Cc1cccc(C)c1CB(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
SCN4A P35499 8/20 0.38
CYP1A2 P05177 3/20 0.38
TSHR P16473 3/20 0.38
LMNA P02545 3/20 0.38
SCN1A P35498 2/20 0.38
SCN5A Q14524 2/20 0.38
SCN9A Q15858 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
NFKB1 P19838 2/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2C9 P11712 1/20 0.38
KCNK3 O14649 1/20 0.38
CACNA1F O60840 1/20 0.38
KCNK2 O95069 1/20 0.38
GBA1 P04062 1/20 0.38
MAOA P21397 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900522 0.75 ESR1 (0.44) ALDH1A1SCN4ACYP1A2TSHRLMNA
SCHEMBL3900176 0.73 TAAR1 (0.46) ALDH1A1TSHRLMNAACHETAAR1
SCHEMBL357603 0.70 GABRA1 (0.48) ALDH1A1CYP1A2TSHRCYP2A6TRPA1
SCHEMBL29953504 0.70 AKR1B1 (0.46) ALDH1A1CYP1A2TSHRLMNACYP3A4
SCHEMBL11739423 0.70 ALDH1A1 (0.42) ALDH1A1CYP1A2TSHRLMNACYP2A6
SCHEMBL3786534 0.70 LIPG (0.37) ALDH1A1SCN4ACYP1A2TSHRLMNA
SCHEMBL8093986 0.69 CYP2A6 (0.47) ALDH1A1CYP1A2TSHRCYP3A4CYP2A6
SCHEMBL5250399 0.69 TAAR1 (0.50) ALDH1A1CYP1A2TSHRCYP2A6TRPA1
SCHEMBL61913 0.67 ALDH1A1 (0.50) ALDH1A1CYP1A2TSHRCYP2A6TRPA1
SCHEMBL8096178 0.67 CYP2A6 (0.45) ALDH1A1CYP1A2TSHRLMNACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836415-A Propionic acid derivative and application thereof in medicine 西藏海思科制药有限公司 2025-04-15 CN disclosed
CN-116554378-A Non-metallocene catalyst, preparation method and application 万华化学集团股份有限公司 2023-08-08 CN disclosed