SCHEMBL3900522

SCHEMBL3900522

Cc1cccc(CB(O)O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TRPA1 O75762 2/20 0.43
ATM Q13315 1/20 0.43
TP53 P04637 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 1/20 0.37
P2RX7 Q99572 1/20 0.37
KDM4C Q9H3R0 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
SCN4A P35499 3/20 0.34
LMNA P02545 2/20 0.34
CYP1A2 P05177 2/20 0.34
TSHR P16473 2/20 0.34
SCN1A P35498 2/20 0.34
SCN5A Q14524 2/20 0.34
SCN9A Q15858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900176 0.82 TAAR1 (0.46) GAAMAPTALDH1A1TAAR1LMNA
SCHEMBL31589756 0.75 ESR1 (0.48) ESR1ESR2TRPA1ATMTP53
SCHEMBL29645271 0.75 PDCD1 (0.57) ESR1ESR2TRPA1ATMTP53
SCHEMBL92946 0.75 PDCD1 (0.57) ESR1ESR2TRPA1ATMTP53
SCHEMBL29080438 0.75 ALDH1A1 (0.42) TRPA1ATMGAAMAPTALDH1A1
SCHEMBL3306785 0.74 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
SCHEMBL6547407 0.74 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
SCHEMBL30231281 0.74 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
Hydrogen Sulfide SCHEMBL3190770 0.73 PDCD1 (0.55) ESR1ESR2TRPA1ATMTP53
Ammonia Solution, Strong SCHEMBL4609369 0.73 PDCD1 (0.55) ESR1ESR2TRPA1ATMTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321628-B Preparation method of beta-dimethylphenyl silicon substituted organic nitrile compound 湖北工程学院 2023-04-28 CN claimed
CN-116731061-A Method for efficiently preparing 1-silicon-based-2-alkyl compound 武汉大学 2023-09-12 CN disclosed
CN-112321628-B Preparation method of beta-dimethylphenyl silicon substituted organic nitrile compound 湖北工程学院 2023-04-28 CN disclosed
CN-112778351-B Preparation method of beta-dimethylphenyl silicon substituted aromatic nitro compound 湖北工程学院 2023-04-28 CN disclosed
CN-111995635-B Method for preparing organosilicon compound by catalyzing chitosan loaded copper film material 湖北工程学院 2023-04-25 CN disclosed
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
WO-2006076020-A2 FUEL COMPOSITIONS AND METHODS THEREOF FERNANDES JOSEPH B (US) 2006-07-20 WO disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050229479-A1 Fuel compositions and methods thereof ETANE USA, L.L.C. 2005-10-20 US disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed