SCHEMBL29080593

SCHEMBL29080593

Br[Mg]Br.O=Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.83
VCAM1 P19320 1/20 0.48
ALDH1A3 P47895 3/20 0.47
HSD17B10 Q99714 1/20 0.44
ALDH3A1 P30838 2/20 0.43
IGF1R P08069 1/20 0.43
NAT1 P18440 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PTGS2 P35354 1/20 0.40
RAB9A P51151 1/20 0.40
PYGL P06737 3/20 0.40
NPFFR2 Q9Y5X5 2/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CHAT P28329 1/20 0.39
KDM4A O75164 1/20 0.39
KDM4B O94953 1/20 0.39
CYP2A6 P11509 1/20 0.38
TTR P02766 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48577 0.91 ALDH1A1 (1.00) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL29364412 0.91 ALDH1A1 (1.00) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
Hydrochloric Acid SCHEMBL28849470 0.89 ALDH1A1 (0.95) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
Hydrochloric Acid SCHEMBL28849465 0.86 ALDH1A1 (0.91) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
Methylene Chloride SCHEMBL27781502 0.84 ALDH1A1 (0.86) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL29433282 0.76 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL1572335 0.76 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL115626 0.76 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL29723741 0.76 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL671268 0.76 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111689995-B High-solubility triaryl carbon borate and preparation method and application thereof 万华化学集团股份有限公司 2023-09-19 CN disclosed