SCHEMBL671268

SCHEMBL671268

O=Cc1ccc(Cl)c(Br)c1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.64
VCAM1 P19320 1/20 0.50
ALDH1A3 P47895 5/20 0.47
HSD17B10 Q99714 2/20 0.46
ALDH3A1 P30838 3/20 0.44
KDM4E B2RXH2 1/20 0.41
PTGS2 P35354 1/20 0.41
RAB9A P51151 1/20 0.41
CYP2A6 P11509 2/20 0.39
TTR P02766 1/20 0.39
TSHR P16473 1/20 0.38
TYR P14679 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
ALDH5A1 P51649 1/20 0.36
ABAT P80404 1/20 0.36
ERN1 O75460 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29723741 1.00 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL23604537 0.84 ALDH1A1 (0.50) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL1572335 0.82 ALDH1A1 (0.64) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL18346095 0.79 XDH (0.48) ALDH1A1VCAM1KDM4ERAB9ATDP1
SCHEMBL18346097 0.79 XDH (0.48) ALDH1A1VCAM1KDM4ERAB9ATDP1
SCHEMBL29364412 0.78 ALDH1A1 (1.00) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL48577 0.78 ALDH1A1 (1.00) ALDH1A1VCAM1ALDH1A3HSD17B10ALDH3A1
SCHEMBL29610150 0.78 ALDH1A3 (0.52) ALDH1A1ALDH1A3HSD17B10ALDH3A1KDM4E
SCHEMBL870202 0.78 ALDH1A3 (0.52) ALDH1A1ALDH1A3HSD17B10ALDH3A1KDM4E
SCHEMBL16959164 0.77 ALDH1A1 (0.43) ALDH1A1KDM4ERAB9ATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569553-A Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2025-03-07 CN claimed
WO-2026107424-A1 N-(4-(IMIDAZO[4,5-B]PYRIDIN-5-YL)-2-PYRIDYL)BENZAMIDE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-21 WO disclosed
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF DEWPOINT THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12612396-B1 Modulators of beta catenin and uses thereof DEWPOINT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
CN-119569553-B Preparation method and application of 3-methoxy-4-chlorobenzaldehyde 苏州亚科科技股份有限公司 2026-04-21 CN disclosed
EP-4262788-B1 UREA OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-20250375526-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-12-11 US disclosed
EP-3483142-B1 AROMATIC ACETYLENE OR AROMATIC ETHYLENE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF BEIJING MAXINOVEL PHARMACEUTICALS CO LTD (CN) 2025-10-15 EP disclosed
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-10-07 US disclosed
US-20250127792-A1 IMIDAZOPIPERAZINE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-04-24 US disclosed
WO-2001083484-A1 PYRANO, PIPERIDINO, AND THIOPYRANO COMPOUNDS AND METHODS OF USE ABBOTT LABORATORIES (US) 2001-11-08 WO disclosed
WO-2001016122-A1 BENZYLIDENE-THIAZOLIDINEDIONES AND ANALOGUES AND THEIR USE IN THE TREATMENT OF DIABETES MAXIA PHARMACEUTICALS, INC. (US) 2001-03-08 WO disclosed
US-6162918-A Xanthene and acridine derivatives HOFFMANN-LA ROCHE INC. (US) 2000-12-19 US disclosed
US-5969139-A INHIBITORS OF HERPES SIMPLEX VIRUS THYMIDINE KINASE HOFFMANN-LA ROCHE INC. (US) 1999-10-19 US disclosed
CN-1228778-A Pyridazino [4,5-b]-quinoline 5-oxide derivatives, their preparation and their use as glycine antagonists MERZ & CO GMBH & CO (DE) 1999-09-15 CN disclosed
WO-1999038833-A1 PROCESS FOR THE HALOGENATION OF ALDEHYDES AND KETONES BROMINE COMPOUNDS LTD. (IL) 1999-08-05 WO disclosed
EP-0931081-A1 PYRIDAZINO 4,5-B]-QUINOLINE 5-OXIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS GLYCINE ANTAGONISTS MERZ + CO. GmbH & Co. (DE) 1999-07-28 EP disclosed
EP-0823426-A1 Xanthene and acridine derivatives and their use F. HOFFMANN-LA ROCHE AG (CH) 1998-02-11 EP disclosed
WO-1998004556-A1 PYRIDAZINO [4,5-B]-QUINOLINE 5-OXIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS GLYCINE ANTAGONISTS MERZ + CO. GMBH & CO. (DE) 1998-02-05 WO disclosed
EP-0074571-A1 Process for the preparation of para-substituted 3-bromobenzaldehydes BAYER AG (DE) 1983-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612396-B1 Modulators of beta catenin and uses thereof CTNNB1, CTNND1, CTNNA1 ALDH1A1 3860/4885VCAM1 3466/4885ALDH1A3 4129/4885
US-20250375526-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ALDH1A1 2776/4885VCAM1 3606/4885ALDH1A3 3176/4885
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 INMT, CARM1, KDM1B ALDH1A1 1178/4885VCAM1 1293/4885ALDH1A3 1288/4885
US-20260138977-A1 MODULATORS OF BETA CATENIN AND USES THEREOF CTNNB1, CTNND1, CTNNA1 ALDH1A1 3860/4885VCAM1 3466/4885ALDH1A3 4129/4885
US-20250127792-A1 IMIDAZOPIPERAZINE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS EP300, CREBBP, RBBP7 ALDH1A1 3232/4885VCAM1 1912/4885ALDH1A3 3243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.