SCHEMBL29433282

SCHEMBL29433282

O=Cc1ccc(O)c(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
KDM4E B2RXH2 1/20 0.64
PTGS2 P35354 1/20 0.64
RAB9A P51151 1/20 0.64
ALDH5A1 P51649 3/20 0.52
ABAT P80404 3/20 0.52
TRIM24 O15164 1/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
HSD17B10 Q99714 2/20 0.50
TTR P02766 1/20 0.50
TSHR P16473 1/20 0.50
BACE1 P56817 1/20 0.50
ALDH1A3 P47895 2/20 0.48
AOX1 Q06278 1/20 0.47
ERN1 O75460 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
VCAM1 P19320 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL115626 1.00 ALDH1A1 (0.64) ALDH1A1KDM4EPTGS2RAB9AALDH5A1
Benzaldehyde SCHEMBL28811827 0.90 ALDH1A1 (0.53) ALDH1A1KDM4EPTGS2RAB9AALDH5A1
SCHEMBL545072 0.82 ALDH1A1 (0.64) ALDH1A1KDM4EPTGS2RAB9AALDH5A1
SCHEMBL9622273 0.81 LCK (0.61) ALDH1A1KDM4ERAB9AHPGDTDP1
SCHEMBL9622274 0.81 LCK (0.61) ALDH1A1KDM4ERAB9AHPGDTDP1
SCHEMBL3768957 0.79 KDM4E (0.46) ALDH1A1KDM4EPTGS2RAB9AALDH5A1
SCHEMBL11001027 0.79 TSHR (0.52) ALDH1A1KDM4EPTGS2RAB9AHPGD
SCHEMBL48577 0.78 ALDH1A1 (1.00) ALDH1A1KDM4EPTGS2RAB9AHSD17B10
SCHEMBL29364412 0.78 ALDH1A1 (1.00) ALDH1A1KDM4EPTGS2RAB9AHSD17B10
Protocatechualdehyde SCHEMBL36350 0.78 KDM4E (1.00) ALDH1A1KDM4EPTGS2RAB9AALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4648762-A2 PPARG MODULATORS University of Florida Research Foundation, Incorporated (US) 2025-11-19 EP disclosed
EP-4584267-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
WO-2024151519-A2 PPARG MODULATORS UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) 2024-07-18 WO disclosed
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
EP-4301752-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2024-01-10 EP disclosed
EP-4214189-A1 AGENTS FOR USE IN THE TREATMENT OF AMYLOIDOSIS UCL Business Ltd (GB) 2023-07-26 EP disclosed
EP-4178557-A1 COMBINATION ANTI-CANCER PRODUCTS AND METHODS Ankh Life Sciences Limited (IE) 2023-05-17 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2022011132-A9 COMBINATION ANTI-CANCER PRODUCTS AND METHODS ANKH LIFE SCIENCES LIMITED (IE) 2022-10-20 WO disclosed
CN-112812113-B Immunomodulatory compounds, compositions and uses thereof 杭州和正医药有限公司 2022-09-20 CN disclosed
WO-2022185041-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-09-09 WO disclosed
EP-4003286-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-06-01 EP disclosed
WO-2022058733-A1 AGENTS FOR USE IN THE TREATMENT OF AMYLOIDOSIS UCL BUSINESS PLC (GB) 2022-03-24 WO disclosed