Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080910 | 0.81 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL18366141 | 0.78 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL29080908 | 0.78 | RIPK1 (0.44) | RIPK1PKM | |
| SCHEMBL18366436 | 0.76 | RIPK1 (0.52) | RIPK1PKM | |
| SCHEMBL29080904 | 0.75 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL18367359 | 0.75 | BACE1 (0.34) | RIPK1 | |
| SCHEMBL18372657 | 0.74 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL22887842 | 0.73 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL18366511 | 0.73 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL18366443 | 0.72 | RIPK1 (0.39) | RIPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |