Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080940 | 0.80 | PKM (0.31) | — | |
| SCHEMBL29080931 | 0.79 | POLB (0.34) | — | |
| SCHEMBL30587548 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL18366415 | 0.77 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL29080903 | 0.76 | NPC1 (0.33) | — | |
| SCHEMBL29080906 | 0.75 | RIPK1 (0.37) | — | |
| SCHEMBL30587563 | 0.74 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL18367373 | 0.74 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL30587642 | 0.72 | RIPK1 (0.38) | — | |
| SCHEMBL18366600 | 0.72 | RIPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |