Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755981 | 0.83 | AGBL2 (0.47) | FFAR4RXRARXRBRXRGNOS3 | |
| SCHEMBL17396703 | 0.83 | AGBL2 (0.47) | FFAR4RXRARXRBRXRGNOS3 | |
| SCHEMBL17396700 | 0.82 | AGBL2 (0.46) | FFAR4RXRARXRBRXRGNOS3 | |
| Hydrochloric Acid SCHEMBL17653893 | 0.82 | AGBL2 (0.46) | FFAR4RXRARXRBRXRGNOS3 | |
| SCHEMBL2771208 | 0.80 | L3MBTL1 (0.53) | SYKALDH1A1GAAL3MBTL1 | |
| Lithium Ion SCHEMBL17396698 | 0.79 | NOS3 (0.44) | NOS3NOS2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL27860893 | 0.79 | ALDH1A1 (0.46) | FFAR4NOS3NOS2TBXA2RALDH1A1 | |
| SCHEMBL29009956 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL17396756 | 0.77 | AGBL2 (0.46) | FFAR4RXRARXRBRXRGNOS3 | |
| SCHEMBL4326563 | 0.77 | ALDH1A1 (0.44) | FFAR4NOS3NOS2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |