Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087925 | 0.74 | RAB9A (0.48) | ALDH1A1SMN1; SMN2CYP1A2RAB9APOLB | |
| SCHEMBL7753230 | 0.74 | CYP1A2 (0.51) | ALDH1A1SMN1; SMN2CYP1A2MAPTRAB9A | |
| SCHEMBL841568 | 0.72 | CYP1A2 (0.61) | ALDH1A1SMN1; SMN2CYP1A2MAPTRAB9A | |
| SCHEMBL3093655 | 0.70 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2CYP1A2MAPTRAB9A | |
| SCHEMBL17595322 | 0.69 | CYP1A2 (0.58) | ALDH1A1SMN1; SMN2CYP1A2MAPTRAB9A | |
| SCHEMBL1424967 | 0.69 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2CYP1A2S1PR2MAPT | |
| SCHEMBL3443140 | 0.69 | CA12 (0.58) | SMN1; SMN2CYP1A2RAB9ANPC1NPSR1 | |
| SCHEMBL3369232 | 0.69 | NLRP3 (0.56) | ALDH1A1SMN1; SMN2CYP1A2MAPTRAB9A | |
| SCHEMBL6509026 | 0.69 | TAS1R3 (0.46) | CYP2C19 | |
| SCHEMBL12853621 | 0.69 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2CYP1A2S1PR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116867758-A | IRAK degradation agents and uses thereof | 凯麦拉医疗公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116669722-A | Interleukin-1 receptor-related kinase (IRAK) degradants and uses thereof | 凯麦拉医疗公司 | 2023-08-29 | — | — | CN | disclosed |