Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29083803 | 0.88 | MAPK10 (0.75) | TSHRALDH1A1MAPK10NR3C2SMN1; SMN2 | |
| SCHEMBL30367058 | 0.83 | RAB9A (0.61) | TSHRALDH1A1NR3C2SMN1; SMN2L3MBTL1 | |
| SCHEMBL15941191 | 0.79 | HPGD (0.56) | TSHRALDH1A1MAPK10L3MBTL1RIOK2 | |
| SCHEMBL31240707 | 0.78 | CYP1A2 (0.58) | TSHRALDH1A1NR3C2SMN1; SMN2KMT2A | |
| SCHEMBL29083771 | 0.78 | F2 (0.64) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL16877226 | 0.78 | SMN1; SMN2 (0.58) | ALDH1A1MAPK10NR3C2SMN1; SMN2L3MBTL1 | |
| SCHEMBL15648214 | 0.77 | FPR2 (0.67) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1555088 | 0.76 | HPGD (0.54) | TSHRALDH1A1MAPK10SMN1; SMN2L3MBTL1 | |
| SCHEMBL29276334 | 0.76 | ALDH1A1 (0.55) | TSHRALDH1A1MAPK10NR3C2SMN1; SMN2 | |
| SCHEMBL1554419 | 0.74 | RIOK2 (0.57) | ALDH1A1SMN1; SMN2L3MBTL1RIOK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |