Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555616 | 0.92 | LMNA (0.48) | KMT2ANT5ENAMPTMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL29928336 | 0.71 | LMNA (0.50) | LMNANPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL5778500 | 0.71 | LMNA (0.50) | MAPK1LMNARAB9ANPSR1 | |
| SCHEMBL20379630 | 0.71 | NAMPT (0.88) | NAMPTCYP3A4MAPK14 | |
| SCHEMBL7717749 | 0.70 | KMT2A (0.47) | KMT2ANT5ENAMPTMAPK1LMNA | |
| SCHEMBL7717745 | 0.70 | KMT2A (0.47) | KMT2ANT5ENAMPTMAPK1LMNA | |
| SCHEMBL26101409 | 0.69 | NAMPT (0.81) | NAMPTMAPK1NPC1RAB9A | |
| SCHEMBL5750238 | 0.68 | KDM4E (0.56) | KMT2ANT5ENAMPTMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL5454019 | 0.68 | KDM4E (0.55) | KMT2ANT5ENAMPTMAPK1LMNA | |
| SCHEMBL11617697 | 0.68 | MAPK1 (1.00) | KMT2ANT5ENAMPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956865-B2 | MEDICINES COMPRISING Rho KINASE INHIBITOR | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-08-18 | — | — | EP | disclosed |
| EP-0956865-B1 | MEDICINES COMPRISING Rho KINASE INHIBITOR | MITSUBISHI PHARMA CORP (JP) | 2007-04-18 | — | — | EP | disclosed |