Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717745 | 1.00 | KMT2A (0.47) | KMT2ANT5ENPC1RAB9AMEN1 | |
| SCHEMBL2908400 | 0.70 | KMT2A (0.56) | KMT2ANT5ENPC1RAB9AMEN1 | |
| SCHEMBL7479134 | 0.69 | ROCK2 (0.56) | KMT2ARAB9AMEN1MAPK1NAMPT | |
| SCHEMBL7479130 | 0.69 | ROCK2 (0.56) | KMT2ARAB9AMEN1MAPK1NAMPT | |
| SCHEMBL5458619 | 0.68 | KDM4E (0.67) | KMT2ANT5EMEN1MAPK1NAMPT | |
| Hydrochloric Acid SCHEMBL29928336 | 0.67 | LMNA (0.50) | NPC1RAB9ALMNAL3MBTL1NPSR1 | |
| (4-Chlorophenyl)(Cyclopropyl)Methanone SCHEMBL392801 | 0.67 | MGLL (0.68) | KMT2AMEN1MGLLLMNATP53 | |
| SCHEMBL12893507 | 0.67 | MGLL (0.71) | KMT2AMEN1MGLL | |
| SCHEMBL5473986 | 0.67 | KDM4E (0.65) | KMT2ANT5EMAPK1NAMPTLMNA | |
| SCHEMBL1554314 | 0.66 | RAB9A (0.44) | RAB9ANAMPTLMNATP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177796-A1 | PREVENTIVES/REMEDIES FOR LIVER DISEASES | Mitsubishi Pharma Corporation (JP) | 2002-02-06 | — | — | EP | disclosed |