SCHEMBL2908459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1549824	0.84	FBP1 (0.58)	FBP1CA12CA1CA2CA7
	SCHEMBL14017881	0.83	HSD17B1 (0.39)	FBP1CA12CA1CA2CA7
	SCHEMBL3930336	0.83	KDM4E (0.45)	CYP3A4KMT2APPARDPPARAPPARG
	SCHEMBL4399378	0.83	RAB9A (0.50)	FBP1TP53RAB9ASMN1; SMN2LMNA
	SCHEMBL13210251	0.83	FBP1 (0.41)	FBP1TP53RAB9ASMN1; SMN2LMNA
	SCHEMBL28657507	0.80	FBP1 (0.51)	FBP1SMN1; SMN2ALDH1A1MAPT
	SCHEMBL2908470	0.79	CNR1 (0.36)	FBP1TP53RAB9ACYP3A4ACHE
	SCHEMBL28694469	0.78	CYP3A4 (0.43)	TP53RAB9ACA12CA1CA2
	SCHEMBL28277544	0.78	FBP1 (0.41)	FBP1CYP3A4PPARDPPARAPPARG
	SCHEMBL2901062	0.78	FBP1 (0.41)	FBP1SMN1; SMN2LMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.