Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941652 | 0.86 | FBP1 (0.56) | FBP1PTGDR2TSHRLMNAALDH1A1 | |
| SCHEMBL2905996 | 0.80 | HSD17B2 (0.36) | FBP1TSHRMAPK1LMNAMAPT | |
| SCHEMBL2908459 | 0.78 | FBP1 (0.42) | FBP1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13210251 | 0.77 | FBP1 (0.41) | FBP1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4399378 | 0.77 | RAB9A (0.50) | FBP1TSHRLMNAALDH1A1MAPT | |
| SCHEMBL739939 | 0.75 | LMNA (0.55) | TSHRMAPK1LMNAALDH1A1MAPT | |
| SCHEMBL28657507 | 0.74 | FBP1 (0.51) | FBP1TSHRALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2907446 | 0.73 | HTT (0.60) | TSHRMAPK1LMNAALDH1A1GAA | |
| SCHEMBL4348248 | 0.73 | KMT2A (0.52) | TSHRLMNAALDH1A1MAPTGAA | |
| SCHEMBL28277544 | 0.72 | FBP1 (0.41) | FBP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951692-B1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-08-18 | — | — | EP | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2010-02-25 | — | — | US | disclosed |
| US-20090088368-A1 | COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS | IRM LLC (BM) | 2009-04-02 | — | — | US | disclosed |
| US-20090088368-A1 | COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS | IRM LLC (BM) | 2009-04-02 | — | — | US | disclosed |
| EP-1979360-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-10-15 | — | — | EP | disclosed |
| EP-1951692-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007089667-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056496-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048453-A1 | OXAZOLE AND THIAZOLE PPAR MODULATOR | PPARD, PPARG, PPARA | FBP1 929/4885PTGDR2 240/4885TSHR 343/4885 |
| US-20090088368-A1 | COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS | PPARG, PPARA, PPARD | FBP1 293/4885PTGDR2 430/4885TSHR 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.