SCHEMBL29085597

SCHEMBL29085597

Fc1ccc(F)c(Bc2c(F)ccc(F)c2F)c1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 2/20 0.35
▸ CES1 P23141 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352628 0.78 ACHE (0.35) —
SCHEMBL6061879 0.75 — —
SCHEMBL5355583 0.73 TUBB1 (0.43) —
SCHEMBL45430 0.71 CES2 (0.53) CES2CES1
SCHEMBL5365866 0.71 CA1 (0.36) CES2CES1
SCHEMBL6063288 0.69 CA1 (0.31) —
SCHEMBL6062359 0.69 — —
SCHEMBL6062440 0.69 RAPGEF4 (0.32) —
SCHEMBL3975406 0.68 CES2 (0.50) CES2CES1
Ammonia Solution, Strong SCHEMBL3047305 0.68 CES2 (0.50) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448476-A1 PROCESS FOR BORANE-MEDIATED ESTER REDUCTION Provivi, Inc. (US) 2024-10-23 — — EP claimed
US-20240082830-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2024-03-14 — — US claimed
EP-4263560-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS AldexChem Kft. (HU) 2023-10-25 — — EP claimed
CN-116685594-A Triarylborane catalysts and methods for selective hydrosilylation of esters and lactones using the same 阿尔迪斯化学有限责任公司 2023-09-01 — — CN claimed
WO-2023114437-A1 PROCESS FOR BORANE-MEDIATED ESTER REDUCTION PROVIVI, INC. (US) 2023-06-22 — — WO claimed
WO-2022129966-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2022-06-23 — — WO claimed
EP-4448476-A1 PROCESS FOR BORANE-MEDIATED ESTER REDUCTION Provivi, Inc. (US) 2024-10-23 — — EP disclosed
US-20240082830-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2024-03-14 — — US disclosed
EP-4263560-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS AldexChem Kft. (HU) 2023-10-25 — — EP disclosed
CN-116685594-A Triarylborane catalysts and methods for selective hydrosilylation of esters and lactones using the same 阿尔迪斯化学有限责任公司 2023-09-01 — — CN disclosed
WO-2023114437-A1 PROCESS FOR BORANE-MEDIATED ESTER REDUCTION PROVIVI, INC. (US) 2023-06-22 — — WO disclosed
WO-2022129966-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2022-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240082830-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS TREH, STS, LSS CES2 204/4885CES1 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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