Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087693 | 1.00 | HIF1A (0.43) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29087751 | 0.89 | HIF1A (0.41) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29087753 | 0.89 | HIF1A (0.41) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL26970080 | 0.87 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29617642 | 0.87 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27136637 | 0.87 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29617606 | 0.87 | L3MBTL1 (0.46) | HIF1AEPAS1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29617617 | 0.80 | L3MBTL1 (0.47) | HIF1AEPAS1L3MBTL1KDM4EFAAH | |
| SCHEMBL29617639 | 0.76 | CHRM2 (0.46) | HIF1AEPAS1KDM4EALDH1A1FAAH | |
| SCHEMBL29087736 | 0.76 | CHRM2 (0.46) | HIF1AEPAS1KDM4EALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |