Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617642 | 1.00 | L3MBTL1 (0.46) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL29617606 | 1.00 | L3MBTL1 (0.46) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL27136637 | 1.00 | L3MBTL1 (0.46) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL29617617 | 0.88 | L3MBTL1 (0.47) | L3MBTL1HIF1AEPAS1KDM4EFAAH | |
| SCHEMBL29087693 | 0.87 | HIF1A (0.43) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL29087696 | 0.87 | HIF1A (0.43) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL4495877 | 0.82 | PSEN1 (0.43) | L3MBTL1KDM4EALDH1A1TEAD1MDM2 | |
| SCHEMBL29087753 | 0.80 | HIF1A (0.41) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL29087751 | 0.80 | HIF1A (0.41) | L3MBTL1HIF1AEPAS1KDM4EALDH1A1 | |
| SCHEMBL4517269 | 0.78 | LMNA (0.42) | HIF1AEPAS1KCNH2SIGMAR1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416202-A1 | Small Molecule Compounds and Compositions | TELO THERAPEUTICS, INC. | 2023-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416202-A1 | Small Molecule Compounds and Compositions | TERT, TP53, EP300 | L3MBTL1 681/4885HIF1A 2084/4885EPAS1 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.