Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459380 | 0.82 | KIF11 (0.65) | KIF11CYP11B1CYP11B2TGM2GSTO1 | |
| SCHEMBL486039 | 0.81 | MKNK1 (0.47) | KIF11CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18459326 | 0.79 | KIF11 (0.53) | KIF11TGM2GSTO1BACE1PPARD | |
| SCHEMBL27522027 | 0.78 | MKNK1 (0.44) | HDAC1MKNK1MKNK2CYP11B1CYP11B2 | |
| SCHEMBL1580568 | 0.78 | CHRNB1 (0.46) | KIF11CHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12085342 | 0.77 | KIF11 (0.56) | KIF11CYP11B1CYP11B2TGM2 | |
| Hydrochloric Acid SCHEMBL27901791 | 0.76 | KIF11 (0.54) | KIF11CYP11B1CYP11B2TGM2 | |
| SCHEMBL29064876 | 0.71 | CES2 (0.45) | KIF11TGM2 | |
| SCHEMBL1843427 | 0.71 | MKNK1 (0.62) | KIF11KDM1AHDAC1MKNK1MKNK2 | |
| SCHEMBL31301420 | 0.71 | MKNK1 (0.62) | KIF11KDM1AHDAC1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |