Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL29088357 | 0.85 | CES2 (0.44) | PARP1MAPTPOLBCYP3A4TSHR | |
| SCHEMBL1425072 | 0.76 | HTT (0.43) | PARP1POLBTSHRBRD4KDM4E | |
| Benzamide SCHEMBL28488657 | 0.76 | PARP1 (0.80) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL27752814 | 0.76 | CYP3A4 (0.80) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL1332331 | 0.76 | — | — | |
| SCHEMBL21755166 | 0.76 | PARP1 (1.00) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL29618402 | 0.76 | — | — | |
| Benzamide SCHEMBL16352 | 0.76 | — | — | |
| Benzamide SCHEMBL1222101 | 0.76 | PARP1 (1.00) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL6690447 | 0.76 | PARP1 (1.00) | PARP1MAPTPOLBCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472268-A | Compounds capable of binding to proteins and conjugates obtained from these compounds | MC SAF公司 | 2023-07-21 | — | — | CN | disclosed |