Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 7/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855403 | 0.77 | KDM4E (0.38) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL2922217 | 0.75 | MAPT (0.49) | TBXAS1AKR1C3PRSS1TMPRSS15APEX1 | |
| SCHEMBL2922214 | 0.75 | MAPT (0.49) | TBXAS1AKR1C3PRSS1TMPRSS15APEX1 | |
| SCHEMBL29088405 | 0.74 | RARB (0.35) | TBXAS1AKR1C3RXRARXRBRXRG | |
| SCHEMBL29088435 | 0.74 | RXRA (0.36) | TBXAS1AKR1C3RXRARXRBRXRG | |
| SCHEMBL22870263 | 0.72 | CA12 (0.39) | HCAR2ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL1705828 | 0.70 | HPGD (0.41) | HCAR3HCAR2APEX1ALDH1A1MAPT | |
| SCHEMBL29088394 | 0.70 | KMT2A (0.39) | AKR1C3RXRARXRBRXRGPRSS1 | |
| SCHEMBL7799437 | 0.68 | PKM (0.49) | TBXAS1AKR1C3PRSS1TMPRSS15APEX1 | |
| SCHEMBL29600076 | 0.68 | LMNA (0.43) | RXRAALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669744-A | Nrf2 activating compounds | 千寿制药株式会社 | 2023-08-29 | — | — | CN | disclosed |