Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722743 | 0.91 | MPO (0.50) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL24528787 | 0.91 | MPO (0.50) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL22075927 | 0.89 | ALDH1A1 (0.48) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL22075960 | 0.88 | MAPT (0.48) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL30369865 | 0.88 | MAPT (0.48) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL31372228 | 0.77 | PARP1 (0.45) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL3657122 | 0.76 | HSD17B10 (0.48) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL25316782 | 0.76 | HSD17B10 (0.48) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL3656194 | 0.76 | HSD17B10 (0.50) | HSD17B10PDK1PDK2PDK3PDK4 | |
| SCHEMBL22075949 | 0.75 | TSHR (0.56) | HSD17B10PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116897150-A | Novel bifunctional molecules for protein-targeted degradation | 安菲斯塔治疗有限公司 | 2023-10-17 | — | — | CN | disclosed |