Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 14/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.64 |
| ▸ | PGR | P06401 | 5/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SHBG | P04278 | 2/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL6 | P05231 | 1/20 | 0.59 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426288 | 0.94 | HIF1A (0.62) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL3999013 | 0.92 | HIF1A (0.67) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL138847 | 0.92 | HIF1A (0.66) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL28809123 | 0.92 | HIF1A (0.66) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL20553193 | 0.91 | HIF1A (0.65) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL6001323 | 0.91 | HIF1A (0.65) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL28715728 | 0.91 | HIF1A (0.69) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL14931695 | 0.90 | HIF1A (0.64) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL249836 | 0.90 | HIF1A (0.64) | HIF1AHSD17B10CYP3A4PGRCYP2C19 | |
| SCHEMBL28553943 | 0.90 | HIF1A (0.64) | HIF1AHSD17B10CYP3A4PGRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916764-A | Fasted mimicking diet promotes cancer-free survival of acute lymphoblastic leukemia models | 南加利福尼亚大学 | 2023-10-20 | — | — | CN | disclosed |