Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15079892 | 0.79 | LMNA (0.53) | POLBL3MBTL1TDP1MTNR1AMTNR1B | |
| SCHEMBL401448 | 0.77 | KDM4E (0.75) | TAAR1POLBL3MBTL1TDP1MTNR1A | |
| SCHEMBL29633165 | 0.77 | TAAR1 (0.69) | TAAR1TDP1LMNACA12CA1 | |
| SCHEMBL39970 | 0.77 | TAAR1 (0.69) | TAAR1TDP1LMNACA12CA1 | |
| SCHEMBL1592409 | 0.77 | CA12 (0.68) | POLBL3MBTL1TDP1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL1623557 | 0.76 | KDM4E (0.79) | TAAR1POLBL3MBTL1TDP1MTNR1A | |
| SCHEMBL6649844 | 0.76 | L3MBTL1 (0.67) | TAAR1POLBL3MBTL1TDP1MTNR1A | |
| Ammonia Solution, Strong SCHEMBL7689341 | 0.75 | TAAR1 (0.67) | TAAR1TDP1LMNACA12CA1 | |
| Hydrochloric Acid SCHEMBL27527127 | 0.75 | TAAR1 (0.67) | TAAR1POLBTDP1LMNACA12 | |
| Hydrochloric Acid SCHEMBL9272901 | 0.75 | TAAR1 (0.67) | TAAR1POLBTDP1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756057-B1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LTD (IN) | 2010-08-04 | — | — | EP | claimed |
| EP-0004920-B1 | DERIVATIVES OF CARBAZOLYL-4-OXYPROPANOLAMINE, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0004920-A1 | Derivatives of carbazolyl-4-oxypropanolamine, methods for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1979-10-31 | — | — | EP | disclosed |